Take I-65 south to the Bardstown/Cleremont exit. Turn left onto highway 245 and go approximately 16 miles (the road will dead end at HWY 150). Turn left onto HWY 150 and go approximately 15 miles and St. Catharine College will be on your right.
Take Bluegrass Parkway west to exit 42 – Springfield/Lebanon. Turn left and go approximately 13 miles to intersection (HWY 555/150). Turn right and St. Catharine College is approximately 2 miles on the left.
Take I-65 north toward Louisville. Take the Bluegrass Parkway (in Elizabethtown) east to the Bardstown/Springfield exit 25. Turn right and go approximately 15 miles and St. Catharine College will be on your right.
Take I-75 north toward Lexington. Take exit 59 which will put you on US HWY 25/150. Turn left and travel approximately 36 miles to Danville. Turn left onto Perryville Road/150 and go approximately 30 miles to HWY 555 and turn left. Go to second light and turn right and St. Catharine College will be approximately 2 miles on your left.